Transfer RNA methyltransferases with a SpoU‐TrmD (SPOUT) fold and their modified nucleosides in tRNA
The existence of SpoU‐TrmD (SPOUT) RNA methyltransferase superfamily was first predicted by bioinformatics. SpoU is the previous name of TrmH, which catalyzes the 2’‐Omethylation of ribose of G18 in tRNA; TrmD catalyzes the formation of N1‐methylguanosine at position 37 in tRNA. Although SpoU (TrmH)...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-02-01
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| Series: | Biomolecules |
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| Online Access: | http://www.mdpi.com/2218-273X/7/1/23 |