Enhanced skin delivery of vismodegib-loaded rigid liposomes combined with ethosomes

Vismodegib, first approved in 2012 for the treatment of basal cell carcinoma, is an inhibitor of the Hedgehog signaling pathway that becomes active in certain tumors. However, its secondary effects after oral administration and systemic distribution are severe. In this study, we loaded vismodegib in...

Full description

Bibliographic Details
Main Authors: E.T. Aguayo Frías, D. Maza Vega, M.N. Calienni, C. Lillo, D.S. Vazquez, S.d.V. Alonso, J. Montanari
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:OpenNano
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352952023000658