Enhanced skin delivery of vismodegib-loaded rigid liposomes combined with ethosomes
Vismodegib, first approved in 2012 for the treatment of basal cell carcinoma, is an inhibitor of the Hedgehog signaling pathway that becomes active in certain tumors. However, its secondary effects after oral administration and systemic distribution are severe. In this study, we loaded vismodegib in...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-11-01
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Series: | OpenNano |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352952023000658 |