Role of immediate early genes in the development of salivary gland organoids in polyisocyanopeptide hydrogels

Human salivary gland organoids have opened tremendous possibilities for regenerative medicine in patients undergoing radiotherapy for the treatment of head and neck cancer. However, their clinical translation is greatly limited by the current use of Matrigel for organoid derivation and expansion. He...

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Bibliographic Details
Main Authors: Paulien Schaafsma, Laura Kracht, Mirjam Baanstra, Anne L. Jellema-de Bruin, Robert P. Coppes
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1100541/full