Optimization of Xenografting Methods for Generating Human Skeletal Muscle in Mice

Xenografts of human skeletal muscle generated in mice can be used to study muscle pathology and to test drugs designed to treat myopathies and muscular dystrophies for their efficacy and specificity in human tissue. We previously developed methods to generate mature human skeletal muscles in immunoc...

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Bibliographic Details
Main Authors: Andrea O’Neill, Anna Llach Martinez, Amber L. Mueller, Weiliang Huang, Anthony Accorsi, Maureen A. Kane, David Eyerman, Robert J. Bloch
Format: Article
Language:English
Published: SAGE Publishing 2024-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/09636897241242624