Semi-Quantitative MALDI Measurements of Blood-Based Samples for Molecular Diagnostics

Semi-Quantitative MALDI Measurements of Blood-Based Samples for Molecular Diagnostics

Accurate and precise measurement of the relative protein content of blood-based samples using mass spectrometry is challenging due to the large number of circulating proteins and the dynamic range of their abundances. Traditional spectral processing methods often struggle with accurately detecting o...

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Bibliographic Details
Main Authors: Matthew A. Koc, Senait Asmellash, Patrick Norman, Steven Rightmyer, Joanna Roder, Robert W. Georgantas, Heinrich Roder
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
proteomics
mass spectrometry
spectral processing
set enrichment analysis
peak detection
Online Access:https://www.mdpi.com/1420-3049/27/3/997

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https://www.mdpi.com/1420-3049/27/3/997

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