Temporal dynamics of a CSF1R signaling gene regulatory network involved in epilepsy.

Colony Stimulating Factor 1 Receptor (CSF1R) is a potential target for anti-epileptic drugs. However, inhibition of CSF1R is not well tolerated by patients, thereby prompting the need for alternative targets. To develop a framework for identification of such alternatives, we here develop a mathemati...

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Bibliographic Details
Main Authors: Claude Gérard, Laurane De Mot, Sabine Cordi, Jonathan van Eyll, Frédéric P Lemaigre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008854