Detection of Nine Oncogenes Amplification in Lung and Colorectal Cancer Formalin-Fixed Paraffin-Embedded Tissue Samples using Combined Next-Generation Sequencing-Based Script and Digital Droplet Polymerase Chain Reaction

Detection of Nine Oncogenes Amplification in Lung and Colorectal Cancer Formalin-Fixed Paraffin-Embedded Tissue Samples using Combined Next-Generation Sequencing-Based Script and Digital Droplet Polymerase Chain Reaction

Introduction Gene copy number variations have theranostic impact and require reliable methods for their identification. We aimed to evaluate the reliability of combined next-generation sequencing (NGS) and digital droplet PCR (ddPCR) method for gene amplification evaluation. Methods We conducted a r...

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Bibliographic Details
Main Authors: Christophe Bontoux MD, Alice Guyard MD, Audrey Lupo MD, PhD, Karim Diallo MSc, Khedidja Rebah MD, Agathe Hercent MD, Edouard Guenzi MD, Jérome Cros MD, PhD, Jérome Lamoril MD, Karen Leroy PharmD, PhD, Nathalie Theou-Anton PharmD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2023-03-01
Series:Cancer Control
Online Access:https://doi.org/10.1177/10732748231167257

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https://doi.org/10.1177/10732748231167257

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