The Alternatively Spliced Isoforms of Key Molecules in the cGAS-STING Signaling Pathway

The Alternatively Spliced Isoforms of Key Molecules in the cGAS-STING Signaling Pathway

Alternative splicing of pre-mRNA increases transcriptome and proteome diversity by generating distinct isoforms that encode functionally diverse proteins, thus affecting many biological processes, including innate immunity. cGAS-STING signaling pathway, whose key molecules also undergo alternative s...

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Bibliographic Details
Main Authors: Jiaqian Liang, Ze Hong, Boyue Sun, Zhaoxi Guo, Chen Wang, Juanjuan Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
alternative splicing
spliced isoforms
cGAS-STING signaling pathway
IFN response
antiviral response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.771744/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.771744/full

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