Whole-brain opto-fMRI map of mouse VTA dopaminergic activation reflects structural projections with small but significant deviations

Abstract Ascending dopaminergic projections from neurons located in the Ventral Tegmental Area (VTA) are key to the etiology, dysfunction, and control of motivation, learning, and addiction. Due to the evolutionary conservation of this nucleus and the extensive use of mice as disease models, establi...

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Bibliographic Details
Main Authors: Horea-Ioan Ioanas, Bechara John Saab, Markus Rudin
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-01812-5