Antioxidant effect of grape seed extract corrects experimental autoimmune encephalomyelitis behavioral dysfunctions, demyelination, and glial activation

Antioxidant effect of grape seed extract corrects experimental autoimmune encephalomyelitis behavioral dysfunctions, demyelination, and glial activation

Background and purposeMultiple sclerosis (MS), a multifactorial autoimmune disease of the central nervous system (CNS), is characterized by demyelination and chronic inflammation, as well as axonal and neuronal loss. There is no cure for MS, and despite a significant improvement in the therapeutic m...

Full description

Bibliographic Details
Main Authors: Maha Mabrouk, Mohamed El Ayed, Amélie Démosthènes, Youssef Aissouni, Ezzedine Aouani, Laurence Daulhac-Terrail, Meherzia Mokni, Mélina Bégou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
experimental autoimmune encephalomyelitis
grape seed extract
oxidative stress
therapeutic approach
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.960355/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.960355/full

Similar Items