Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus
Wnt proteins mediate embryonic development but how protein localization and patterning is regulated is unclear. Here, the authors show that distinct structures with different heparan sulfate modifications (‘N-sulfo-rich’ and ‘N-acetyl-rich’) regulate cellular localization and signal transduction of...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-12-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-017-02076-0 |