Conformational change of apolipoprotein A-I and HDL formation from model membranes under intracellular acidic conditions

Conformational change of apolipoprotein A-I and HDL formation from model membranes under intracellular acidic conditions

The molecular mechanism by which nascent HDL forms via the interaction of apolipoprotein A-I (apoA-I) and transmembrane ABCA1 is poorly understood. Here, because ABCA1 has been reported to localize to acidic intracellular compartments, including the Golgi and endosome, we studied the interaction of...

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Bibliographic Details
Main Authors: Masakazu Fukuda, Minoru Nakano, Masakazu Miyazaki, Masafumi Tanaka, Hiroyuki Saito, Satoe Kobayashi, Masaharu Ueno, Tetsurou Handa
Format: Article
Language:English
Published: Elsevier 2008-11-01
Series:Journal of Lipid Research
Subjects:
endosome
Golgi
phosphatidylcholine
phosphatidylserine
reconstituted HDL
translocase activity
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520346198

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http://www.sciencedirect.com/science/article/pii/S0022227520346198

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