Simulation and Stability Assessment of Anti-EpCAM Immunotoxin for Cancer Therapy
Purpose: Epithelial cell adhesion molecule (EpCAM) is a dominant antigen in human colon carcinoma tissue. Topology features of this antigen are different in normal and malignant conditions; for instance, EpCAM is much less accessible to antibodies in normal cells than in cancerous tissues. Hence, Ep...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2018-08-01
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Series: | Advanced Pharmaceutical Bulletin |
Subjects: | |
Online Access: | http://apb.tbzmed.ac.ir/PDF/apb-8-447.pdf |