Simulation and Stability Assessment of Anti-EpCAM Immunotoxin for Cancer Therapy

Simulation and Stability Assessment of Anti-EpCAM Immunotoxin for Cancer Therapy

Purpose: Epithelial cell adhesion molecule (EpCAM) is a dominant antigen in human colon carcinoma tissue. Topology features of this antigen are different in normal and malignant conditions; for instance, EpCAM is much less accessible to antibodies in normal cells than in cancerous tissues. Hence, Ep...

Full description

Bibliographic Details
Main Authors: Seyed-Ali Hosseinian, Aliakbar Haddad-Mashadrizeh, Samaneh Dolatabadi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-08-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
EpCAM
Cancer therapy
Immunotoxin
Simulation
Stability
Online Access:http://apb.tbzmed.ac.ir/PDF/apb-8-447.pdf

Similar Items

Similar Items