Interface analysis of the complex between ERK2 and PTP-SL.

Interface analysis of the complex between ERK2 and PTP-SL.

The activity of ERK2, an essential component of MAP-kinase pathway, is under the strict control of various effector proteins. Despite numerous efforts, no crystal structure of ERK2 complexed with such partners has been obtained so far. PTP-SL is a major regulator of ERK2 activity. To investigate the...

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Bibliographic Details
Main Authors: Mihaela C Balasu, Laurentiu N Spiridon, Simona Miron, Constantin T Craescu, Axel J Scheidig, Andrei-Jose Petrescu, Stefan E Szedlacsek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2675061?pdf=render

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http://europepmc.org/articles/PMC2675061?pdf=render

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