Diethyl nitrosamine-induces neurobehavioral deficit, oxido-nitrosative stress in rats' brain: a neuroprotective role of diphenyl diselenide

Abstract Diethylnitrosamine (DEN), a common dietary carcinogen, is associated with neurotoxicity in humans and animals. This study investigated the neuroprotective effects of diphenyl diselenide (DPDS) against DEN-induced neurotoxicity in male Albino Wistar rats (n = 40). Rats were randomly distribu...

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Bibliographic Details
Main Authors: Solomon Owumi, Joseph Chimezie, Praise Dyap Emmanuel, Anthony Chukwuma Okeibuno, Olatunde Owoeye
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Neuroscience
Subjects:
Online Access:https://doi.org/10.1186/s12868-024-00922-8