Effects of chemotherapy on contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers: A nationwide cohort study

Effects of chemotherapy on contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers: A nationwide cohort study

Aim: BRCA1/2 mutation carriers with primary breast cancer (PBC) are at high risk of contralateral breast cancer (CBC). In a nationwide cohort, we investigated the effects of chemotherapeutic agents given for PBC on CBC risk separately in BRCA1 and BRCA2 mutation carriers. Patients and methods: BRCA1...

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Bibliographic Details
Main Authors: Delal Akdeniz, Mark van Barele, Bernadette A.M. Heemskerk-Gerritsen, Ewout W. Steyerberg, Michael Hauptmann, Irma van de Beek, Klaartje van Engelen, Marijke R. Wevers, Encarnacion B. Gómez García, Margreet G.E.M. Ausems, Lieke P.V. Berger, Christi J. van Asperen, Muriel A. Adank, Margriet J. Collée, Denise J. Stommel-Jenner, Agnes Jager, Marjanka K. Schmidt, Maartje J. Hooning
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Breast
Subjects:
Breast cancer
Secondary
Risk factors
Chemotherapy
BRCA1
BRCA2
Online Access:http://www.sciencedirect.com/science/article/pii/S0960977621010134

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http://www.sciencedirect.com/science/article/pii/S0960977621010134

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