In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines

In Silico and In Vitro Studies of Novel Azomethines on DNA Repair Genes in Gastric Cell Lines

We herein report the determination of the cytotoxic activity and expression profiles of some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The studied novel compounds were synthesized by a condensation reaction and received compounds were characterized by &...

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Bibliographic Details
Main Authors: Alpaslan Ozturk, Tugba Agbektas, Alakbar Huseynzada, Ruslan Guliyev, Rana Ganbarova, Ulviyya Hasanova, Ayca Tas, Sultan Erkan, Cemile Zontul, Nihal Inandiklioglu, Yavuz Silig
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Life
Subjects:
azomethine group
cytotoxicity
DNA repair gene
gastric cancer
gene expression
molecular docking
Online Access:https://www.mdpi.com/2075-1729/13/10/1982

Internet

https://www.mdpi.com/2075-1729/13/10/1982

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