Clonally expanded cytotoxic CD4+ T cells and the pathogenesis of IgG4-related disease
IgG4-related disease (IgG4-RD) is a systemic condition of unknown cause characterized by highly fibrotic lesions, with dense lymphoplasmacytic infiltrates containing a preponderance of IgG4-expressing plasma cells. CD4+ T cells and B cells constitute the major inflammatory cell populations in IgG4-R...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2017-01-01
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Series: | Autoimmunity |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/08916934.2017.1280029 |