8-Gene signature related to CD8+ T cell infiltration by integrating single-cell and bulk RNA-sequencing in head and neck squamous cell carcinoma

8-Gene signature related to CD8+ T cell infiltration by integrating single-cell and bulk RNA-sequencing in head and neck squamous cell carcinoma

Background: CD8+ T cells, a critical component of the tumor immune microenvironment, have become a key target of cancer immunotherapy. Considering the deficiency of robust biomarkers for head and neck squamous cell carcinoma (HNSCC), this study aimed at establishing a molecular signature associated...

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Bibliographic Details
Main Authors: Shoujing Zhang, Wenyi Zhang, Jian Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Genetics
Subjects:
CD8+ T cells
head and neck squamous cell carcinoma
immunotherapy
prognosis
weighted gene co-expression network analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.938611/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.938611/full

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