Target lysis by cholesterol extraction is a rate limiting step in the resolution of phagolysosomes

The ongoing phagocytic activity of macrophages necessitates an extraordinary capacity to digest and resolve incoming material. While the initial steps leading to the formation of a terminal phagolysosome are well studied, much less is known about the later stages of this process, namely the degradat...

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Bibliographic Details
Main Authors: Dante Barreda, Sergio Grinstein, Spencer A. Freeman
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:European Journal of Cell Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0171933523000973