HMGA2 promotes cancer metastasis by regulating epithelial–mesenchymal transition

HMGA2 promotes cancer metastasis by regulating epithelial–mesenchymal transition

Epithelial–mesenchymal transition (EMT) is a complex physiological process that transforms polarized epithelial cells into moving mesenchymal cells. Dysfunction of EMT promotes the invasion and metastasis of cancer. The architectural transcription factor high mobility group AT-hook 2 (HMGA2) is high...

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Bibliographic Details
Main Authors: Qing Ma, Sisi Ye, Hong Liu, Yu Zhao, Yan Mao, Wei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Oncology
Subjects:
HMGA2
epithelial-mesenchymal transition
extracellular matrix
cancer
gene therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1320887/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2024.1320887/full

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