Current research in pathophysiology of opioid-induced respiratory depression, neonatal opioid withdrawal syndrome, and neonatal antidepressant exposure syndrome
Respiratory depression (RD) is the primary cause of death due to opioids. Opioids bind to mu (µ)-opioid receptors (MORs) encoded by the MOR gene Oprm1, widely expressed in the central and peripheral nervous systems including centers that modulate breathing. Respiratory centers are located throughout...
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Format: | Article |
Language: | English |
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Elsevier
2022-01-01
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Series: | Current Research in Toxicology |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2666027X22000159 |