Liver X receptors induce antiproliferative effects in basal‐like breast cancer

Liver X receptors induce antiproliferative effects in basal‐like breast cancer

Liver X receptors (LXRs) are nuclear transcription factors important in the regulation of cholesterol transport, and glucose and fatty acid metabolism. The antiproliferative role of LXRs has been studied in a variety of malignancies and may represent a therapeutic opportunity in cancers lacking targ...

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Bibliographic Details
Main Authors: Mads Haugland Haugen, Hedda von der Lippe Gythfeldt, Eivind Valen Egeland, Lisa Svartdal Normann, Abhilash D. Pandya, Lise‐Lotte Vedin, Siri Juell, Ellen Tenstad, Geir Frode Øy, Alexandr Kristian, Elisabetta Marangoni, Therese Sørlie, Knut Steffensen, Gunhild Mari Mælandsmo, Olav Engebraaten
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Molecular Oncology
Subjects:
basal‐like breast cancer
LXR
PDX
RPPA
Online Access:https://doi.org/10.1002/1878-0261.13476

Internet

https://doi.org/10.1002/1878-0261.13476

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