Eomes function is conserved between zebrafish and mouse and controls left-right organiser progenitor gene expression via interlocking feedforward loops

Eomes function is conserved between zebrafish and mouse and controls left-right organiser progenitor gene expression via interlocking feedforward loops

The T-box family transcription factor Eomesodermin (Eomes) is present in all vertebrates, with many key roles in the developing mammalian embryo and immune system. Homozygous Eomes mutant mouse embryos exhibit early lethality due to defects in both the embryonic mesendoderm and the extraembryonic tr...

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Bibliographic Details
Main Authors: Conor D. Talbot, Mark D. Walsh, Stephen J. Cutty, Randa Elsayed, Eirini Vlachaki, Ashley E. E. Bruce, Fiona C. Wardle, Andrew C. Nelson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Eomes
T-box
vgll4l
left-right organiser
zebrafish
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.982477/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.982477/full

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