Exposure of the Basophilic Cell Line KU812 to Liposomes Reveals Activation Profiles Associated with Potential Anaphylactic Responses Linked to Physico-Chemical Characteristics

Exposure of the Basophilic Cell Line KU812 to Liposomes Reveals Activation Profiles Associated with Potential Anaphylactic Responses Linked to Physico-Chemical Characteristics

Lipidic nanoparticles (LNP), particularly liposomes, have been proven to be a successful and versatile platform for intracellular drug delivery for decades. Whilst primarily developed for small molecule delivery, liposomes have recently undergone a renaissance due to their success in vaccination str...

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Bibliographic Details
Main Authors: Alexander J. Plant-Hately, Burcu Eryilmaz, Christopher A. W. David, Danielle E. Brain, Bethany J. Heaton, Yvonne Perrie, Neill J. Liptrott
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
basophil
lipidic nanoparticles
liposomes
anaphylaxis
complement activation-related pseudoallergy
Online Access:https://www.mdpi.com/1999-4923/14/11/2470

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https://www.mdpi.com/1999-4923/14/11/2470

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