Small Molecule Anti-biofilm Agents Developed on the Basis of Mechanistic Understanding of Biofilm Formation

Small Molecule Anti-biofilm Agents Developed on the Basis of Mechanistic Understanding of Biofilm Formation

Microbial biofilms are the cause of persistent infections associated with various medical implants and distinct body sites such as the urinary tract, lungs, and wounds. Compared with their free living counterparts, bacteria in biofilms display a highly increased resistance to immune system activitie...

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Bibliographic Details
Main Authors: Katrine Qvortrup, Louise Dahl Hultqvist, Martin Nilsson, Tim Holm Jakobsen, Charlotte Uldahl Jansen, Jesper Uhd, Jens Bo Andersen, Thomas E. Nielsen, Michael Givskov, Tim Tolker-Nielsen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Chemistry
Subjects:
Pseudomonas aeruginosa
Escherichia coli
Acinetobacter baumannii
c-di-GMP
pilicides and curlicides
quorum sensing
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00742/full

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https://www.frontiersin.org/article/10.3389/fchem.2019.00742/full

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