Vasorelaxation, Induced by Dictyota pulchella (Dictyotaceae), a Brown Alga, Is Mediated via Inhibition of Calcium Influx in Rats

Vasorelaxation, Induced by Dictyota pulchella (Dictyotaceae), a Brown Alga, Is Mediated via Inhibition of Calcium Influx in Rats

This study aimed to investigate the cardiovascular effects elicited by Dictyota pulchella, a brown alga, using in vivo and in vitro approaches. In normotensive conscious rats, CH2Cl2/MeOH Extract (CME, 5, 10, 20 and 40 mg/kg) from Dictyota pulchella produced dose-dependent hypotension (−4 ± 1; −8 ±...

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Bibliographic Details
Main Authors: Isac A. Medeiros, George E. C. Miranda, José M. Barbosa-Filho, Valdir A. Braga, Maria C. Alustau, Camila S. Figueiredo, Fabíola F. Furtado, Abrahão A. Oliveira-Filho, Natália T. Machado, Thyago M. Queiroz
Format: Article
Language:English
Published: MDPI AG 2011-10-01
Series:Marine Drugs
Subjects:
calcium
hypotension
mesenteric artery
vasodilatation
Online Access:http://www.mdpi.com/1660-3397/9/10/2075/

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http://www.mdpi.com/1660-3397/9/10/2075/

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