Biomarker discovery by integrated joint non-negative matrix factorization and pathway signature analyses

Abstract Predictive biomarkers are important for selecting appropriate patients for particular treatments. Comprehensive genomic, transcriptomic, and pharmacological data provide clues for understanding relationships between biomarkers and drugs. However, it is still difficult to mine biologically m...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Naoya Fujita, Shinji Mizuarai, Katsuhiko Murakami, Kenta Nakai
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Nature Portfolio 2018-06-01
Σειρά:Scientific Reports
Διαθέσιμο Online:https://doi.org/10.1038/s41598-018-28066-w