Antibody Response to Influenza Hemagglutinin Conserved Stalk Domain after Sequential Immunization with Old Vaccine Strains

Hemagglutinin (HA) is the major envelope glycoprotein and antigen on the surface of influenza virions. The glycoprotein comprises a globular head and a stalk region. While immunodominant epitopes on influenza HA head are highly variable, the stalk domain is conserved. The variability of the HA head...

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Bibliographic Details
Main Authors: Alita Kongchanagul, Promsin Masrinoul, Chompunuch Boonarkart, Ornpreya Suptawiwat, Prasert Auewarakul
Format: Article
Language:English
Published: Hindawi Limited 2024-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2024/5691673