IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells

Multiple myeloma (MM) is a hematological malignancy originating from malignant and clonally expanding plasma cells. MM can be molecularly stratified, and its clonal evolution deciphered based on the Ig heavy and light chains of the respective malignant plasma cell clone. Of all MM subtypes, IgE type...

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Bibliographic Details
Main Authors: Sebastian Uhrig, Carsten Müller-Tidow, Stefan Fröhling, Hartmut Goldschmidt, Michael Platten, Michael Hundemer, Niklas Kehl, Michael Kilian, Julius Michel, Tim R Wagner, Alexander Brobeil, Lilli-Sophie Sester, Sven Blobner, Simon Steiger, Niels Weinhold, Karsten Rippe, Stefan B Eichmüller, Lukas Bunse, Marc-Steffen Raab, Mirco J Friedrich
Format: Article
Language:English
Published: BMJ Publishing Group 2022-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/10/e005815.full