BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis

BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis

Abstract VEGF inhibitors are one of the most successful antiangiogenic drugs in the treatment of many solid tumors. Nevertheless, pancreatic adenocarcinoma (PAAD) cells can reinstate tumor angiogenesis via activation of VEGF-independent pathways, thereby conferring resistance to VEGF inhibitors. Bio...

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Bibliographic Details
Main Authors: Chongbiao Huang, Hui Li, Yang Xu, Chao Xu, Huizhi Sun, Zengxun Li, Yi Ge, Hongwei Wang, Tiansuo Zhao, Song Gao, Xiuchao Wang, Shengyu Yang, Peiqing Sun, Zhe Liu, Jing Liu, Antao Chang, Jihui Hao
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01478-5

Internet

https://doi.org/10.1038/s41392-023-01478-5

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