Does intervention with GLP-1 receptor agonist semaglutide modulate perception of sweet taste in women with obesity: study protocol of a randomized, single-blinded, placebo-controlled clinical trial

Does intervention with GLP-1 receptor agonist semaglutide modulate perception of sweet taste in women with obesity: study protocol of a randomized, single-blinded, placebo-controlled clinical trial

Abstract Background Preclinical studies demonstrated that glucagon-like peptide 1 (GLP-1) is locally synthesized in taste bud cells and that GLP-1 receptor exists on the gustatory nerves in close proximity to GLP-1-containing taste bud cells. This local paracrine GLP-1 signalling seems to be specifi...

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Bibliographic Details
Main Authors: Mojca Jensterle, Simona Ferjan, Tadej Battelino, Jernej Kovač, Saba Battelino, Dušan Šuput, Andrej Vovk, Andrej Janež
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Trials
Subjects:
Semaglutide
Taste
Gustatory coding
PCOS
Obesity
Online Access:https://doi.org/10.1186/s13063-021-05442-y

Internet

https://doi.org/10.1186/s13063-021-05442-y

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