Activation of the Rat α1β2ε GABA<sub>A</sub> Receptor by Orthosteric and Allosteric Agonists

Activation of the Rat α1β2ε GABA<sub>A</sub> Receptor by Orthosteric and Allosteric Agonists

GABA<sub>A</sub> receptors are a major contributor to fast inhibitory neurotransmission in the brain. The receptors are activated upon binding the transmitter GABA or allosteric agonists including a number of GABAergic anesthetics and neurosteroids. Functional receptors can be formed by...

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Bibliographic Details
Main Authors: Allison L. Germann, Ariel B. Burbridge, Spencer R. Pierce, Gustav Akk
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biomolecules
Subjects:
GABA<sub>A</sub> receptor
activation
potentiation
orthosteric agonist
allosteric agonist
Online Access:https://www.mdpi.com/2218-273X/12/7/868

Internet

https://www.mdpi.com/2218-273X/12/7/868

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