Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment

Transcriptional factor EB regulates macrophage polarization in the tumor microenvironment

Tumor microenvironment (TME) contains a variety of infiltrating immune cells. Among them, tumor-associated macrophages (TAMs) and their alternative activation contribute greatly to the progression of tumors. The mechanisms governing macrophage polarization in the TME are unclear. Here, we show that...

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Bibliographic Details
Main Authors: Liang Fang, Johnie Hodge, Fatma Saaoud, Junfeng Wang, Stephen Iwanowycz, Yuzhen Wang, Yvonne Hui, Trent D. Evans, Babak Razani, Daping Fan
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:OncoImmunology
Subjects:
breast cancer
macrophage
polarization
tfeb
tumor microenvironment
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1312042

Internet

http://dx.doi.org/10.1080/2162402X.2017.1312042

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