Combination therapy with DHA and BMSCs suppressed podocyte injury and attenuated renal fibrosis by modulating the TGF-β1/Smad pathway in MN mice

Combination therapy with DHA and BMSCs suppressed podocyte injury and attenuated renal fibrosis by modulating the TGF-β1/Smad pathway in MN mice

Artemisinin has immunomodulatory, anti-inflammatory, and antifibrotic effects. Some studies have demonstrated that artemisinins have a protective effect on the kidney. DHA is a derivative of artemisinin and has effects similar to those of artemisinin. Human bone marrow-derived mesenchymal stem cells...

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Bibliographic Details
Main Authors: Yongzhang Li, Suzhi Chen, Jinchuan Tan, Yan Zhou, Meifang Ren, Qian Zhang, Meijiao Zhao, Guodong Yuan, Wenxi Zhang, Fengwen Yang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Renal Failure
Subjects:
Membranous nephropathy
dihydroartemisinin
bone marrow mesenchymal stem cells
podocyte injury
renal fibrosis
TGF-β1/Smad
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2022.2120821

Internet

https://www.tandfonline.com/doi/10.1080/0886022X.2022.2120821

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