B-cell-specific MhcII regulates microbiota composition in a primarily IgA-independent manner

B-cell-specific MhcII regulates microbiota composition in a primarily IgA-independent manner

BackgroundThe expression of major histocompatibility complex class II (MhcII) molecules on B cells is required for the development of germinal centers (GCs) in lymphoid follicles; the primary sites for the generation of T-cell-dependent (TD) antibody responses. Peyer’s patches (PPs) are secondary ly...

Full description

Bibliographic Details
Main Authors: Mary Melissa Roland, Tori E. Peacock, Nia Hall, Ahmed Dawood Mohammed, Ryan Ball, Amy Jolly, Sergei Alexeev, Nicolas Dopkins, Mitzi Nagarkatti, Prakash Nagarkatti, Jason L. Kubinak
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
microbiota
MhcII
adaptive immunity
IgA
microbial ecology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1253674/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1253674/full

Similar Items