Whole-genome sequencing reveals the evolutionary trajectory of HBV-related hepatocellular carcinoma early recurrence

Abstract Patients with hepatocellular carcinoma (HCC) have poor long-term survival following curative resection because of the high rate of tumor early recurrence. Little is known about the trajectory of genomic evolution from primary to early-recurrent HCC. In this study, we performed whole-genome...

Full description

Bibliographic Details
Main Authors: Shao-Lai Zhou, Zheng-Jun Zhou, Cheng-Li Song, Hao-Yang Xin, Zhi-Qiang Hu, Chu-Bin Luo, Yi-Jie Luo, Jia Li, Zhi Dai, Xin-Rong Yang, Ying-Hong Shi, Zheng Wang, Xiao-Wu Huang, Jia Fan, Jian Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2022-01-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00838-3