Computational multiplex panel reduction to maximize information retention in breast cancer tissue microarrays.

Recent state-of-the-art multiplex imaging techniques have expanded the depth of information that can be captured within a single tissue sample by allowing for panels with dozens of markers. Despite this increase in capacity, space on the panel is still limited due to technical artifacts, tissue loss...

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Bibliographic Details
Main Authors: Luke Ternes, Jia-Ren Lin, Yu-An Chen, Joe W Gray, Young Hwan Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010505