Cell-autonomous reduction of CYFIP2 changes dendrite length, dendritic protrusion morphology, and inhibitory synapse density in the hippocampal CA1 pyramidal neurons of 17-month-old mice

The cytoplasmic FMR1-interacting protein 2 (CYFIP2) have diverse molecular functions in neurons, including the regulation of actin polymerization, mRNA translation, and mitochondrial morphology and function. Mutations in the CYFIP2 gene are associated with early-onset epilepsy and neurodevelopmental...

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Bibliographic Details
Main Authors: Yoonhee Kim, Ruiying Ma, Yinhua Zhang, Hyae Rim Kang, U Suk Kim, Kihoon Han
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Animal Cells and Systems
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19768354.2024.2360740