Metabolic engineering of low-pH-tolerant non-model yeast, Issatchenkia orientalis, for production of citramalate

Metabolic engineering of low-pH-tolerant non-model yeast, Issatchenkia orientalis, for production of citramalate

Methyl methacrylate (MMA) is an important petrochemical with many applications. However, its manufacture has a large environmental footprint. Combined biological and chemical synthesis (semisynthesis) may be a promising alternative to reduce both cost and environmental impact, but strains that can p...

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Bibliographic Details
Main Authors: Zong-Yen Wu, Wan Sun, Yihui Shen, Jimmy Pratas, Patrick F. Suthers, Ping-Hung Hsieh, Sudharsan Dwaraknath, Joshua D. Rabinowitz, Costas D. Maranas, Zengyi Shao, Yasuo Yoshikuni
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Metabolic Engineering Communications
Subjects:
Poly(methyl methacrylate) (PMMA)
Issatchenkia orientalis
Citramalate
Acid tolerance
Transposon
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030123000032

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http://www.sciencedirect.com/science/article/pii/S2214030123000032

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