ZDHHC16 restrains osteogenic differentiation of bone marrow mesenchymal stem cells by inhibiting phosphorylation of CREB

Aims: The osteogenesis of human bone marrow mesenchymal stem cells (hBMSCs) plays a critical role in fracture healing. Osteogenic differentiation is regulated by a variety of post-translational modifications, but the function of protein palmitoylation in osteogenesis remains largely unknown. Methods...

Full description

Bibliographic Details
Main Authors: Zhiwei Li, Yuan Cheng, Xiangyun Jin, Feiyan Wang, Xinyi Wang, Shenghe Liu, Chao Zhang
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022040762