The structural basis of ATP as an allosteric modulator.

Adenosine-5'-triphosphate (ATP) is generally regarded as a substrate for energy currency and protein modification. Recent findings uncovered the allosteric function of ATP in cellular signal transduction but little is understood about this critical behavior of ATP. Through extensive analysis of...

Full description

Bibliographic Details
Main Authors: Shaoyong Lu, Wenkang Huang, Qi Wang, Qiancheng Shen, Shuai Li, Ruth Nussinov, Jian Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4161293?pdf=render