Checkpoint TIPE2 Limits the Helper Functions of NK Cells in Supporting Antitumor CD8+ T Cells

Checkpoint TIPE2 Limits the Helper Functions of NK Cells in Supporting Antitumor CD8+ T Cells

Abstract Natural killer (NK) cells not only are innate effector lymphocytes that directly participate in tumor surveillance but are also essential helpers in the antitumor CD8+ T‐cell response. However, the molecular mechanisms and potential checkpoints regulating NK cell helper functions remain elu...

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Bibliographic Details
Main Authors: Jiacheng Bi, Xiaomeng Jin, Chaoyue Zheng, Chen Huang, Chao Zhong, Xiaohu Zheng, Zhigang Tian, Haoyu Sun
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Advanced Science
Subjects:
checkpoint inhibition
natural killer cells
Tbx21
Tnfaip8l2
tumor immunity
Online Access:https://doi.org/10.1002/advs.202207499

Internet

https://doi.org/10.1002/advs.202207499

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