Mechanism of HIF-1α Promoting Malignant Development of Nasopharyngeal Carcinoma by Upregulating PD-L1 Under Hypoxic Conditions

Mechanism of HIF-1α Promoting Malignant Development of Nasopharyngeal Carcinoma by Upregulating PD-L1 Under Hypoxic Conditions

Objective To explore the mechanism of HIF-1α promoting malignant development of nasopharyngeal carcinoma by upregulating PD-L1 expression under hypoxic conditions. Methods CNE2 cells were divided into normoxia (20%O2), hypoxia (1%O2), HIF-1α-siRNA+hypoxia and NC-siRNA+hypoxia groups. Cell proliferat...

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Bibliographic Details
Main Authors: JIANG Doudou, DONG Jiawen, HU Desheng, ZHOU Yajuan
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2021-06-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
pd-l1
hif-1α
nasopharyngeal carcinoma
hypoxia
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2021.20.1543.htm

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http://html.rhhz.net/ZLFZYJ/html/8578.2021.20.1543.htm

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