Butyrate Prevents Induction of CXCL10 and Non-Canonical IRF9 Expression by Activated Human Intestinal Epithelial Cells via HDAC Inhibition

Butyrate Prevents Induction of CXCL10 and Non-Canonical IRF9 Expression by Activated Human Intestinal Epithelial Cells via HDAC Inhibition

Non-communicable diseases are increasing and have an underlying low-grade inflammation in common, which may affect gut health. To maintain intestinal homeostasis, unwanted epithelial activation needs to be avoided. This study compared the efficacy of butyrate, propionate and acetate to suppress IFN-...

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Bibliographic Details
Main Authors: Sandra G. P. J. Korsten, Laura Peracic, Luka M. B. van Groeningen, Mara A. P. Diks, Herman Vromans, Johan Garssen, Linette E. M. Willemsen
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
intestinal epithelial cells
short chain fatty acids
CXCL10
STAT1 pathway
Online Access:https://www.mdpi.com/1422-0067/23/7/3980

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https://www.mdpi.com/1422-0067/23/7/3980

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