MiR-199a-3p-regulated alveolar macrophage-derived secretory autophagosomes exacerbate lipopolysaccharide-induced acute respiratory distress syndrome

MiR-199a-3p-regulated alveolar macrophage-derived secretory autophagosomes exacerbate lipopolysaccharide-induced acute respiratory distress syndrome

PurposeAcute respiratory distress syndrome (ARDS) is a prevalent illness in intensive care units. Extracellular vesicles and particles released from activated alveolar macrophages (AMs) assist in ARDS lung injury and the inflammatory process through mechanisms that are unclear. This study investigat...

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Bibliographic Details
Main Authors: Xinyi Xu, Xu Liu, Xuecheng Dong, Yi Yang, Ling Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
secretory autophagosome
alveolar macrophage
miR-199a-3p
RAB8A
PAK4
acute respiratory distress syndrome
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1061790/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1061790/full

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