TMEM63B channel is the osmosensor required for thirst drive of interoceptive neurons

TMEM63B channel is the osmosensor required for thirst drive of interoceptive neurons

Abstract Thirst plays a vital role in the regulation of body fluid homeostasis and if deregulated can be life-threatening. Interoceptive neurons in the subfornical organ (SFO) are intrinsically osmosensitive and their activation by hyperosmolarity is necessary and sufficient for generating thirst. H...

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Bibliographic Details
Main Authors: Guolin Yang, Min Jia, Guizhou Li, Yan-Yu Zang, Yang-Yang Chen, Yue-Ying Wang, Shi-Yu Zhan, Shi-Xiao Peng, Guoqiang Wan, Wei Li, Jian-Jun Yang, Yun Stone Shi
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Discovery
Online Access:https://doi.org/10.1038/s41421-023-00628-x

Internet

https://doi.org/10.1038/s41421-023-00628-x

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