Lifespan Analysis of Dystrophic mdx Fast-Twitch Muscle Morphology and Its Impact on Contractile Function

Lifespan Analysis of Dystrophic mdx Fast-Twitch Muscle Morphology and Its Impact on Contractile Function

Duchenne muscular dystrophy is caused by the absence of the protein dystrophin from skeletal muscle and is characterized by progressive cycles of necrosis/regeneration. Using the dystrophin deficient mdx mouse model, we studied the morphological and contractile chronology of dystrophic skeletal musc...

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Bibliographic Details
Main Authors: Leonit Kiriaev, Sindy Kueh, John W. Morley, Kathryn N. North, Peter J. Houweling, Stewart I. Head
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Physiology
Subjects:
Duchenne muscular dystrophy (DMD)
fiber branching
extensor digitorum longus (EDL)
eccentric contraction
mdx
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.771499/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.771499/full

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