429 Spatial Investigation of the Extracellular Matrix Metastatic Niche in Invasive Breast Cancer by Mass Spectrometry Imaging

OBJECTIVES/GOALS: Metastasis to regional areas decreases invasive breast cancer (IBC) survival rate by 13%. Despite the clinical importance of lymph node involvement, the role of extracellular matrix (ECM) remodeling in metastases is unknown. We hypothesize that the spatial dysregulation of the coll...

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Bibliographic Details
Main Authors: Taylor S Hulahan, Yeonhee Park, Laura Spruill, Hari Nakshatri, Marvella Ford, Peggi M Angel
Format: Article
Language:English
Published: Cambridge University Press 2024-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866124003716/type/journal_article